Dynamics of changes in biochemical composition of blood using isoflurane anesthesia in spinal patients

DOI 10.33861/2071-8020-2021-6-37-39

Kozlov N. A., Gryadunova F. A.

Summary. Under the influence of anesthesia on the body of a dog with neurological deficit, the body functions used in spinal operations change. The conditioning of functional changes is associated with the influence of anesthetic drugs, invasive manipulations, artificial myoplegia, hypothermia, hypotension, ataraxia, artificial ventilation of the lungs, which are included in the anesthetic manual. It is also facilitated by the combination of many drugs for premedication, induction, maintenance of anesthesia and drip infusion. Blood tests before anesthesia are performed to assess metabolic function, monitor drug toxicity during drug treatment, and screen for various diseases in animals. Neurological pathology of the spinal column is urgent. The need for early diagnosis, localization of the lesion, MRI and surgery are associated with anesthesia and possible postoperative complications from the cardiovascular system after anesthesia. The purpose of the surgical operation performed in spinal animals is to decompress the spinal cord. A retrospective analysis of blood biochemical parameters was carried out before anesthesia, after, 24 hours, a month after anesthesia, and the effect of the anesthetic treatment scheme on the change in these blood parameters was assessed. The study was conducted on 50 animals. All patients were divided into 2 groups: experimental (dogs with heart disease) and control (clinically healthy). After conducting this study, we can conclude that the scheme of anesthetic aid seems to be adequate in terms of its effect on changes in these biochemical parameters in the blood.

Keywords: anesthetic aid, isoflurane, ultrasound, computed tomography, magnetic resonance imaging, alanine aminotransferase, aspartate aminotransferase, urea, creatinine, bilirubin.

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Author affiliation:

Kozlov Nikolay A., D.Sc. in Veterinary Medicine, professor of the Department of veterinary surgery of the Moscow State Academy of Veterinary Medicine and Biotechnology named after K.I. Skryabin; 23, аkademika Skryabina st., Moscow, 109472; phone: 8-495-3776986; e-mail: nikvet@mail.ru.

Responsible for correspondence with the editorial board: Gryadunova Faina A., graduate student of the Department of veterinary surgery of the Moscow State Academy of Veterinary Medicine and Biotechnology named after K.I. Skryabin; 23, Akademika Skryabina st., Moscow, 109472; phone: 8-925-8638747; e-mail: fainakuznetcova@mail.ru.