Caprine arthritis-encephalitis: early diagnostics topical issues

УДК 619:616-078: 578.828.61
DOI 10.33861/2071-8020-2023-2-23-25

Kolbasova O. L., Bespalova T. Yu., Korogodina E. V., Krasnova E. A.

Summary. According to the World Organization for Animal Health, the spread of caprine arthritis-encephalitis is most pronounced in industrialized countries and coincides with the movement vectors of European dairy breeds of goats. In connection with the importation of high-milk goats to Russia from abroad, there are certain risks of the spread of the disease. Small ruminant lentiviruses have characteristics that affect diagnosis and transmission, and knowledge of these should be taken into account when planning disease control and eradication programs in goat farms. The authors present up-to-date information on the intrauterine transmission of goat arthritis-encephalitis virus, the features of seroconversion in infected animals and the diagnosis of this disease in the framework of topical issues for goat breeders. Early diagnosis of caprine arthritis is paramount to eradicate the disease and confirm the welfare status of caprine arthritisencephalitis-free areas and farms, and accurate knowledge of transmission routes is an essential component of control programs. The problem of early diagnosis of caprine arthritis-encephalitis in newborn goatlings is particularly relevant. The article provides an analysis of modern scientific research on intrauterine transmission of the caprine arthritis-encephalitis virus, reflects the features of seroconversion in infected animals and highlights the main problems of diagnosing the disease. Answers to topical questions of goat breeders are of great practical importance for planning the rehabilitation of goat farms from CAEV of by the method of ‘sterile delivery’.

Keywords: small ruminants, lentiviruses of small ruminants, goat arthritis-encephalitis, enzyme immunoassay, diffusion gel precipitation test, polymerase chain reaction, seroconversion, intrauterine transmission, newborn goatlings, ‘sterile delivery’.

References:

1. Kolbasova O. L., Egorova I. Yu. Sravnitelnaya otsenka diagnosticheskoy znachimosti IFA test-sistem dlya diagnostiki lentivirusov melkikh zhvachnykh zhivotnykh [Comparative evaluation of the diagnostic significance of ELISA test systems for the diagnosis of lentiviruses in small ruminants]. -Veterinariya. - Moscow, 2020. - No. 6. - pp. 19-23.

2-28. Vide supra.

Author affiliation:

Bespalova Tatyana Yu., deputy head of the research group of the Samara Research Veterinary Institute - Branch of the Federal Scientific Research Center for Virology and Microbiology; 8, Magnitogorskaya st., Samara, 443013; phone: 8-917-1042646; e-mail: 27bt@mail.ru.

Korogodina Elena V., scientific researcher of the Samara Research Veterinary Institute - Branch of the Federal Scientific Research Center for Virology and Microbiology; 8, Magnitogorskaya st., Samara, 443013; phone: 8-937-7977092; e-mail: elenakorogodina@inbox.ru.

Krasnova Elena A., Ph.D. in Biology, Scientific Secretary of the Samara Research Veterinary Institute - Branch of the Federal Scientific Research Center for Virology and Microbiology; 8, Magnitogorskaya st., Samara, 443013; phone: 8-917-1144569; e-mail: novitchkova@rambler.ru.

Responsible for correspondence with the editorial board: Kolbasova Olga L., Ph.D. in Biology, docent, Head of the Department of the Laboratory of Molecular Virology of the Federal Scientific Research Center for Virology and Microbiology; 1, Akademika Bakulova st., Volginsky vllg., Petushinskiy district, Vladimir region, 601125; phone: 8-910-0930563; e-mail: olgakolbasova@gmail.com.