Method of treatment of laboratory animals with mallophagosis

УДК 576.89
DOI 10.33861/2071-8020-2024-1-28-31

Marchenko A. P., Mironova A. A., Svyatogorova A. E., Zubenko A. A., Fetisov L. N., Avagyan E. N.

Summary. A new effective method of combating mallophagosis in laboratory animals and a preparation for its implementation, including dialdehydes, quaternary ammonium salts and excipients, have been proposed. It has been experimentally established that the composition of the proposed composition used as an entomocidal agent in mallophagosis of laboratory rats and other laboratory animals is active against the pathogen Trichodectes spp., causing a decrease in the number of all age stages of the parasite after the first treatment, and complete release of animals after the subsequent one. The proposed composition is low toxic for warm-blooded animals. The result objectively manifested expansion of the spectrum of entomocidal agents for the treatment of laboratory animals with mallophagoses (rabbits, rats, mice). Authors established efficacy of veterinary measures for the invasive disease. The introduction of two types of quaternary ammonium salts, two dialdehydes and excipients (low molecular weight alcohols) into the composition of the drug used in the implementation of the claimed method increased entomocidal activity, including against insects of the genus Trichodectes, while there was a decrease in the infection rate of animals by an average of 80% after the first treatment and until complete release from parasites after the next one.

Keywords: mallophagosis, laboratory mice, guinea pigs, itching of the skin, hyperemia, skin scraping, egg, nymph, adult, entomocidal effectiveness.

Author affiliation:

Marchenko Aleksandr P., junior scientific researcher of the Federal Rostov Agricultural Research Center; 0, Rostov hghw., Novocherkassk, Rostov region, 346421; phone: 8-918-1593306; e-mail: marchenko.alex94@yandex.ru.

Mironova Anna A., D. Sc. in Veterinary Medicine, chief scientific researcher of the Federal Rostov Agricultural Research Center; 0, Rostov hghw., Novocherkassk, Rostov region, 346421; phone: 8-903-4718275; e-mail: aa_mironova@mail.ru.

Zubenko Aleksandr A., D. Sc. in Biology, chief scientific researcher of the Federal Rostov Agricultural Research Center; 0, Rostov hghw., Novocherkassk, Rostov region, 346421; phone: 8-928-6049743; e-mail: alexsandrzubenko@yandex.ru.

Fetisov Leonid N., Ph. D. in Veterinary Medicine, leading scientific researcher of the Federal Rostov Agricultural Research Center; 0, Rostov hghw., Novocherkassk, Rostov region, 346421; phone: 8-908-1978224; e-mail: fetisoff.leonid2018@yandex.ru.

Avagyan Elen N., postgraduate student, laboratory researcher of the Federal Rostov Agricultural Research Center; 0, Rostov hghw., Novocherkassk, Rostov region, 346421; phone: 8-908-1882434; e-mail: elen.avagyan.1999@inbox.ru.

Responsible for correspondence with the editorial board: Svyatogorova Aleksandra E., Ph. D. in Agriculture, scientific researcher of the Federal Rostov Agricultural Research Center; 0, Rostov hghw., Novocherkassk, Rostov region, 346421; phone: 8-988-9525755; e-mail: sviatogorova.a@yandex.ru.